Tag: genetic

By iwano@_84

How coronavirus’s genetic code can help control outbreaks

Scroll to continue arrow-down

The six British patients seemed to have little in common besides this: Each was dealing with kidney failure, and each had tested positive for the coronavirus.

They were among scores of virus-stricken people showing up at Addenbrooke’s Hospital in Cambridge in the early weeks of April. Had they lived in the United States instead of the United Kingdom, the link that allowed the contagion to spread among them might have slipped by unnoticed.

But the U.K. had done something in the early days of the pandemic that the United States and many other nations had not. It funded a national push to repeatedly decode the coronavirus genome as it made its way across the country. The process reveals tiny, otherwise invisible changes in the virus’s genetic code, leaving a fingerprint that gives scientists valuable glimpses into how the disease is spreading. It’s a cutting-edge technique that

Read More
By iwano@_84

The Health 202: Genetic tracing could show how coronavirus spread through White House

White House spokesman Judd Deere said tracing has been done for people who had contact with Trump. But it’s the kind recommended by the Centers for Disease Control and Prevention, which involves merely tracking people who were nearby those known to be infected.

“Contact tracing has been done by the White House Medical Unit consistent with CDC guidelines,” Deere said, though The Post has reported many of the hundreds of people potentially exposed to the president found out via media reports of his diagnosis.

Coding coronavirus samples would give a clear picture of whether recent White House events were so-called “superspreaders.”

This is an approach researchers have tried around the country.

They’ve watched the virus accumulate a catalogue of mutations as it moved through Zip codes in the Houston area. They’ve used genetic sequencing to trace how the virus spread outward from a conference in Boston, infecting people from Alaska

Read More
By iwano@_84

Penn Medicine researchers discover a rare genetic form of dementia

IMAGE

IMAGE: Abnormal neurofibrillary tangles (NFTs) — a buildup of tau protein in parts of the brain — helped Edward Lee, MD, PhD, an assistant professor of Pathology and Laboratory Medicine, and…
view more 

Credit: Edward Lee

PHILADELPHIA — A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain — which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer’s Disease — that could be targeted for new therapies. The study was published today in Science.

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by a buildup of proteins, called tau proteins, in certain parts of the brain. Following an examination of human brain tissue samples from a deceased donor with an unknown neurodegenerative disease, researchers discovered a novel mutation in

Read More
By iwano@_84

Combining machine learning tools for medical imaging with genetic sequencing nets Sophia Genetics $110M

SOPHiA GENETICS, the shoutily and poorly capitalized named startup that’s combining machine learning tools for medical imaging and genetic sequencing to come up with a more holistic view of diseases for better patient care, has raised $110 million in new funding.

The Series F round for the company was led by aMoon an Israeli healthcare and life sciences investment fund, and HItachi Ventures, the investment arm of the Hitachi Group.

Financial services firms like Credit Suisse and the PIctet Group, along with previous investors including Swisscom Ventures, Endeavour Vision, Generation Investment Management, and Eurazeo Growth also participated in the financing.

The company’s technology uses multiple sources of medical data to come up with potentially novel insights about how diseases spread in the body and offer better ways to coordinate care among different . The Boston and Lausanne, Switzerland-based company’s tech is currently used by over 1,000 healthcare institutions and has

Read More