Tag: Typical

By iwano@_84

Slow Lung Decline Typical in Systemic Sclerosis

The interstitial lung disease that develops in a subset of patients with systemic sclerosis tends to be heterogeneous, with the majority of patients experiencing a slow pattern of decline in lung function, analysis of outcomes in the European Scleroderma Trials and Research (EUSTAR) database found.

Among patients with available lung function data for 12 months of follow-up, 12% had significant progression of decline in forced vital capacity (FVC), meaning a decline of more than 10%; 15% had moderate progression (decline of 5% to 10%); 48% were stable (decline or improvement of less than 5%); and 25% showed improvement (increase of 5% or more), noted Oliver Distler, MD, of University Hospital Zurich in Switzerland, and colleagues.

And over 5 years of follow-up, 58% of patients showed a slow pattern of decline, with more 12-month periods of stability or improvement than of decline, the researchers reported in their study online in Annals

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